December 2019

Joint and dose‐dependent associations between aerobic and muscle‐strengthening activity with anxiety: A cross‐sectional study of 1.48 million adults between 2011 and 2017

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Research has shown that regular physical activity is key for the prevention and/or treatment of depression. However, epidemiological studies describing the associations between different physical activity modes (i.e., aerobic vs. muscle‐strengthening exercise) with depression are limited.


Cross‐sectional analyses were conducted on pooled data from four U.S. health surveillance surveys (2011–2017). Validated survey items assessed self‐reported moderate‐to‐vigorous‐intensity physical activity (MVPA) and muscle‐strengthening activity (MSA). Twenty groups were created, ranging from (a) “inactive” (0 MVPA min/week & MSA 0 times/week) to (xx) “most active” (≥300 MVPA min/week & MSA ≥4 times/week). Poisson regression with a robust error variance was used to assess prevalence ratios (PRs) of self‐reported clinically diagnosed depression (outcome variable) across physical activity groups (exposure variables).


The sample contained 1,477,981 adults (≥18 years), of which 286,325 (18.0%) had depression. Compared to the reference group (i.e., no MVPA and no MSA), almost all physical activity combinations were associated with lower depression prevalence. Lowest prevalence of depression was shown for those combining sufficient MVPA–MSA (MVPA ≧300 min/week and MSA ≥2 times/week; adjusted prevalence ratio range: 0.54–0.63). All associations remained after stratification and/or adjustment for sociodemographic (age, sex, income, education), lifestyle characteristics (body mass index, self‐rated health, smoking, alcohol), comorbidities (e.g., arthritis, diabetes, hypertension), and year of survey.


A physical activity routine that includes both aerobic and MSA is likely to be optimal for the prevention of depression. Public health approaches targeting depression should endorse joint aerobic and MSA as key lifestyle modification strategy.

Genetic Pathways Causing Fatty Liver and Atherogenic Dyslipidemia

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Conditions:   Non-alcoholic Fatty Liver;   Atherogenic Dyslipidemia;   Insulin Resistance
Intervention:   Diagnostic Test: Lipoprotein kinetics
Sponsors:   Marja-Riitta Taskinen;   Göteborg University
Enrolling by invitation

[In Focus] Helena Teede: driving collaboration and impact

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“Researchers need to move beyond competition and isolated knowledge generation, towards collaboration and real-world impact”, Helena Teede tells The Lancet Diabetes & Endocrinology. Throughout her career, Teede has been working to drive large-scale collaborative partnerships to deliver impactful research and translation. She is a professor of women's health and director of the Monash Centre for Health Research and Implementation at Monash University, director of Monash Partners Academic Health Science Centre, and an endocrinologist at Monash Health (all in Melbourne, VIC, Australia).

Beef Tartare caused Wisconsin Salmonella Outbreak

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The Wisconsin Department of Health Services (DHS), in collaboration with the La Crosse County Health Department, investigated an outbreak of salmonellosis associated with consuming beef tartare served at Restore Public House in La Crosse between July 10 and July 12, 2019.

35 restaurant patrons were interviewed during the investigation. Seven confirmed and 10 probable (ill but not tested) cases were linked to this outbreak.

Restore Public House voluntarily removed the beef tartare dish from their menu once they were notified of the illnesses.

See the DHS salmonellosis fact sheet for more information on common symptoms of salmonellosis. If you have any symptoms of salmonellosis, please contact your doctor.

Consumption of raw or undercooked meat, poultry, or eggs can increase your risk of foodborne illness. See the DHS food safety webpage for more information on safe food practices.