Hyoscine Vs Metoclopramide

Posted in Gastrointestinal, Medications by Dr Ryan

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Interesting thing that I realised during my course (Graduate Diploma for Family Physician) is that we should not prescribe hyoscine (commonly known as buscopan) together with metoclopramide (maxalon). The reason is because hyoscine is an anti-spasmodic medication which stops abdominal cramps, and metoclopramide has prokinetic properties which helps with gastric emptying (therefore, prevents vomitting).

When you take both of them together, their properties are negated and none of them works! Or they might not work as well as if you take either one on its own!