[Comment] Measuring polysubstance use over the life course: implications for multilevel interventions


Non-medical use of prescription drugs, such as opioids, stimulants, and sedatives or tranquilisers, has increased substantially since 2000.1 Compared to other age groups in the USA, young adults (aged 18–25 years) report the highest prevalence of non-medical use of prescription drugs in the past year (15·3%),2 binge drinking in the past month (36·9%),2 or illicit drug use in the past month (24·2%).2 Polysubstance use in the past year is also common in young adults,3 which increases their risks for negative consequences, including substance use disorder and overdose.


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