Structure-function Relationship in Advanced Glaucoma After Reaching the RNFL Floor

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image Précis:
Although the circumpapillary retinal nerve fiber layer (cpRNFL) got to the dimension floor, the nasal macular area is necessary for analyzing main aesthetic feature in advanced glaucoma.
To explore the relationship in between the main aesthetic area (VF) and also macular specifications acquired from spectral-domain optical comprehensibility tomography (SD-OCT) in clients with advanced glaucoma that got to the cpRNFL density dimension floor and also to identify whether the architectural adjustments gauged by SD-OCT serve for approximating the practical condition in these clients.
A total amount of 68 eyes from 68 clients with advanced glaucoma were consisted of. Just eyes having a typical cpRNFL density of ≤57 μm that got to the dimension floor were consisted of. Macular imaging making use of Cirrus SD-OCT and also 10 -2 Humphrey VF was executed. The VF suggest discrepancy was transformed to a straight range making use of unlogged 1/Lambert worths. The connections in between the main VF and also different macular specifications were established.
Clients had a mean VF suggest discrepancy of −2069 dB and also a typical cpRNFL density of 51.76 ± 3.61 μm. Connections in between the VF and also all cpRNFL density specifications were not substantial. Nevertheless, substantial connections were located in between the main VF and also superonasal macular ganglion cell-inner plexiform layer density (r= 0.334; P= 0.003), internal nasal macular density (r= 0.301; P= 0.013), and also external nasal macular density (r= 0.331; P= 0.007).
Final thoughts:
Also after the cpRNFL had actually gotten to the dimension floor, a number of macular specifications revealed a statistically substantial relationship with practical condition in VF. Specifically, the evaluation of architectural adjustments in the nasal macular area might be essential in identifying the main VF in advanced glaucoma.

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